Guides
Biological age, functional markers, and prevention signals that help explain how aging is being measured.
The most useful longevity guides help people understand measurement, not chase magic numbers. This hub tracks the biological age tools, disease prediction markers, and healthspan metrics that matter most in the current conversation, along with their limits.
Epigenetic Clocks
DNA methylation-based biological age estimates. The most studied class of biomarkers for measuring biological rather than chronological age.
Inflammatory Markers
Signals associated with chronic inflammation and aging risk. Elevated chronic inflammation is linked to accelerated biological aging.
VO2 Max
Cardiorespiratory fitness marker associated with healthspan and mortality risk. One of the strongest predictors of longevity in otherwise healthy adults.
Grip Strength
Functional strength marker often associated with aging outcomes. Declining grip strength correlates with increased all-cause mortality risk.
Telomere Length
Length of protective caps on chromosomes that shorten with age. Controversial as a standalone biomarker due to high variability.
Glucose Regulation
Blood sugar control markers that reflect metabolic aging. Chronic glucose dysregulation accelerates multiple aging pathways.
Proteomic Aging Clocks
Blood plasma protein-based biological age estimates, a newer complement to DNA methylation clocks. Some versions estimate aging rate for individual organs rather than the body as a whole.
Gait Speed
Usual walking speed, a simple functional marker with a long track record in geriatric medicine for predicting mobility decline and mortality risk.
Body Composition (Visceral Fat)
The proportion of fat stored around internal organs versus elsewhere in the body. Elevated visceral fat is more strongly linked to metabolic and cardiovascular aging risk than overall body weight.